Dr. Novel missense variant L46Q of fatty acid synthase gene and fatty acids content in Awassi sheep

نویسندگان

چکیده

This study was conducted to investigate the association between polymorphism of FASN gene with fatty acid content in Awassi sheep. A total 100 male sheep ages one and two a half years old were used this study. Phenotypic measurement recorded at slaughter, from each animal, longissimus dorsi (LD) muscle samples taken analyze profile. Genotyping, sequencing reactions, silico tools performed confirm variants amplified fragments. The result genotyping revealed genotypes (AA AB) ovine (exon 3). Novel SNP (L46Q) discovered only within (AB genotype). All utilized remarkably deleterious effects for L46Q on mutant protein structure, function, stability. Association analysis that AB genotype has significantly (p < 0.05) higher levels animal length monounsaturated acids (MUFA) lower amounts saturated (SFA) than AA genotype. In conclusion, novel genotype), made animals associated good meat quality traits may serve as markers quality.

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ژورنال

عنوان ژورنال: Acta Scientiarum. Animal Sciences

سال: 2022

ISSN: ['1806-2636', '1807-8672']

DOI: https://doi.org/10.4025/actascianimsci.v44i1.56273